Recent publications

Recent publications

Recent Publications (since 2012)


Note: the researchers’ personal web page may contain more recent publications.
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    Lab Members

  • Jacques Bélair (Université de Montréal)
  • Mathieu Blanchette (McGill University)
  • Maurice Chacron (McGill University)
  • Erik Cook (McGill University)
  • Morgan Craig (Université de Montréal)
  • Paul François (McGill University)
  • Frédéric Guichard (McGill University)
  • Antony R. Humphries (McGill University)
  • Anmar Khadra (McGill University)
  • Svetlana V. Komarova (McGill University)
  • Frithjof Lutscher (Université d’Ottawa)
  • Michael C. Mackey (McGill University)
  • Fahima Nekka (Université de Montréal)
  • Christopher Pack (McGill University)
  • Lea Popovic (Concordia University)
  • Alain Vinet (Université de Montréal)


  • Jacques Bélair

    Book chapters:

    • Wu, J., Campbell, S. A., Blair, J., Time-delayed neural networks: stability and oscillations, in Encyclopedia of Computational Neuroscience, D. Jaeger, R. Jung, d., New York, Springer, 2015.

    Peer-reviewed journal articles:

    • Provencher Langlois, G., Craig, M., Humphries, A. R., Mackey, M. C., Mahaffy, J., Blair, J., Moulin, T., Sinclair, S. R., Wang, L., Normal and pathological dynamics of platelets in humans, Journal of Mathematical Biology, 75:6-7 (dcembre 2017), 1411–1462.
    • Vronneau-Veilleux, F., Blair, J., Modeling circadian fluctuations of pharmacokinetic parameters, Mathematical Modelling of Natural Phenomena, 12:5 (2017), 146–161.
    • Abdelrazec, A., Blair, J., Shan, C., Zhu, H., Modeling the spread and control of dengue with limited public health resources, Mathematical Biosciences, 271 (janvier 2016), 136–145.
    • Craig, M., Humphries, A. R., Nekka, F., Blair, J., Li, J., Mackey, M. C., Neutrophil dynamics during concurrent chemotherapy and G-CSF administration: Mathematical modelling guides dose optimisation to minimise neutropenia, Journal of Theoretical Biology, 385 (novembre 2015), 77–89.
    • Blair, J., Yuan, Y., Threshold dynamics in an SEIRS model with latency and temporary immunity, Journal of Mathematical Biology, 69:4 (octobre 2014), 875–904.



    Mathieu Blanchette

    Peer-reviewed journal articles:

    • Gagnon, Y., Blanchette, M., El-Mabrouk, N. S., A flexible ancestral genome reconstruction method based on gapped adjacencies, BMC Bioinformatics, 13:Suppl.19 (dcembre 2012), S4.

    Peer-reviewed conference proceedings:

    • Blanchette, M., Kim, E., Vetta, A., Clique cover on sparse networks, in 2012 Proceedings of the Fourteenth Workshop on Algorithm Engineering and Experiments (ALENEX), Meeting on Algorithm Engineering & Experiments — ALENEX12 (Kyoto, 2012), David A. Bader, Dort Mutzel, d., Philadelphia, PA, SIAM, 2012, 93–102.



    Maurice Chacron

    Peer-reviewed journal articles:

    • Metzen, M. G., Avila Akerberg, O., Chacron, M., Coding stimulus amplitude by correlated neural activity, Physical Review E. Statistical, Nonlinear, and Soft Matter Physics, 91:4 (avril 2015), 042717, 6p.
    • Metzen, M. G., Jamali, M., Carriot, J., Avila Akerberg, O., Cullen, K., Chacron, M., Coding of envelopes by correlated but not single-neuron activity requires neural variability, Proceedings of the National Academy of Sciences of the United States of America, 112:15 (avril 2015), 4791–4796.
    • Metzen, M. G., Chacron, M., Neural heterogeneities determine response characteristics to second-, but not first-order stimulus features, The Journal of Neuroscience, 35:7 (fvrier 2015), 3124–3138.
    • Simmonds, B., Chacron, M., Activation of parallel fiber feedback by spatially diffuse stimuli reduces signal and noise correlations via independent mechanisms in a cerebellum-like structure , PLoS Computational Biology, 11:1 (janvier 2015), e1004034, 15p.
    • Carriot, J., Jamali, M., Chacron, M., Cullen, K., Statistics of the vestibular input expirienced during natural self-motion: implications for neural processing, The Journal of Neuroscience, 34:24 (juin 2014), 8347–8357.
    • Larson, E., Metzen, M. G., Chacron, M., Serotonin modulates electrosensory processing and behavior via 5-HT2-like receptors, Neuroscience, 271 (juin 2014), 108–118.
    • Khosravi-Hashemi, N., Chacron, M., Motion processing across multiple topographic maps in the electrosensory system, Physiological Reports, 2:3 (mars 2014), e00253, 13p.
    • Metzen, M. G., Chacron, M., Weakly electric fish display behavioral responses to envelopes naturally occurring during movement: implications for neural processing, The Journal of Experimental Biology, 217 (2014), 1381–1391.
    • Deemyad, T., Metzen, M. G., Pan, Y., Chacron, M., Serotonin selectively enhances perception and sensory neural responses to stimuli generated by same-sex conspecifics, Proceedings of the National Academy of Sciences of the United States of America, 110:48 (novembre 2013), 19609–19614.
    • Jamali, M., Carriot, J., Chacron, M., Cullen, K., Strong correlations between sensitivity and variability give rise to constant discrimination thresholds across the otolith afferent population, The Journal of Neuroscience, 33:27 (juillet 2013), 11302–11313.
    • Stamper, S. A., Fortune, E. S., Chacron, M., Perception and coding of envelopes in weakly electric fishes, The Journal of Experimental Biology, 216 (juillet 2013), 2393–2402.
    • Toscano Marquez, B., Krahe, R., Chacron, M., Neuromodulation of early electrosensory processing in gymnotiform weakly electric fish, The Journal of Experimental Biology, 216 (2013), 2442–2450.
    • Deemyad, T., Kroeger, J., Chacron, M., Sub-and suprathreshold adaptation currents have opposite effects on frequency tuning, The Journal of Physiology, 590:19 (octobre 2012), 4839–4858.
    • Litwin-Kumar, A., Chacron, M., Doiron, B., The spatial structure of stimuli shapes the timescale of correlations in population spiking activity, PLoS Computational Biology, 8:9 (septembre 2012), e1002667,15p.
    • Massot, C., Schneider, A., Chacron, M., Cullen, K., The vestibular system implements a linear-nonlinear transformation in order to encode self-motion, PLOS Biology, 10:7 (juillet 2012), e1001365, 20p.
    • Khosravi-Hashemi, N., Chacron, M., Bursts and isolated spikes code for opposite movement directions in midbrain electrosensory neurons, PLoS One, 7:6 (juin 2012), e40339,19p.
    • McGillivray, P., Vonderschen, K., Fortune, E. S., Chacron, M., Parallel coding of first-and second-order stimulus attributes by midbrain electrosensory neurons, The Journal of Neuroscience, 32:16 (avril 2012), 5510–5524.



    Erik Cook

    Book chapters:

    • Smith, J., Masse, N. Y., Zhan, C. a., Cook, E., Linking neural activity to visual perception: separating sensory and attentional contributions, in Visual Cortex- Current Status and Perspectives, Stephane Molotchnikoff, Jean Rouat, d., InTech, 2012.

    Peer-reviewed journal articles:

    • Smith, J., Farah, K. N., Cook, E., ROC-Based estimates of neural-behaviral covariations using matched filters, Neural Computation, 26:8 (aot 2014), 1667–1689.
    • Schoen, A., Salehiomran, A., Larkum, M. E., Cook, E., A compartmental model of linear resonance and signal transfer in dendrites, Neural Computation, 24:12 (dcembre 2012), 3126–3144.
    • Sadeghi Ghandehari, N., Pariyadath, V., Apte, S., Eagleman, D. M., Cook, E., Neural correlates of subsecond time distortion in the middle temporal area of visual cortex, Journal of Cognitive Neuroscience, 23:12 (dcembre 2012), 3829–3840.
    • Hacking, S. A., Boyraz, P., Kucharski, W., Brown, C. A., Sen-Gupta, E., Cook, E., Powers, B. M., Surface roughness enhances the osseointegration of titanium headposts in non-human primates, Journal of Neuroscience Methods, 211:2 (novembre 2012), 237–244.
    • Cook, E., Pack, C., Parietal cortex signals come unstuck in time, PLOS Biology, 10:10 (octobre 2012), e1001414.
    • Masse, N. Y., Herrignton, T. M., Cook, E., Spatial attention enhances the selective integration of activity from area MT, Journal of Neurophysiology, 108:6 (septembre 2012), 1594–1606.



    Morgan Craig

    Peer-reviewed journal articles:

    • Provencher Langlois, G., Craig, M., Humphries, A. R., Mackey, M. C., Mahaffy, J., Blair, J., Moulin, T., Sinclair, S. R., Wang, L., Normal and pathological dynamics of platelets in humans, Journal of Mathematical Biology, 75:6-7 (dcembre 2017), 1411–1462.
    • Craig, M., Humphries, A. R., Mackey, M. C., A mathematical model of granulopoiesis incorporating the negative feedback dynamics and kinetics of G-CSF/neutrophil binding and internalization, Bulletin of Mathematical Biology, 78:12 (dcembre 2016), 2304–2357.
    • Craig, M., Gonzlez-Sales, M., Li, J., Nekka, F., Approaching pharmacometrics as a paleontologist would: Recovering the links between drugs and the body through reconstruction, CPT: Pharmacometrics & Systems Pharmacology, 5:3 (mai 2016), 158–160.
    • Craig, M., Humphries, A. R., Nekka, F., Blair, J., Li, J., Mackey, M. C., Neutrophil dynamics during concurrent chemotherapy and G-CSF administration: Mathematical modelling guides dose optimisation to minimise neutropenia, Journal of Theoretical Biology, 385 (novembre 2015), 77–89.



    Paul François

    Book chapters:

    • Francois, P., Evolution in silico: from network structure to bifurcation theory, in Evolutionary Systems Biology, Soyer, Orkun S., d., Advances in Experimental Medicine and Biology, Vol. 751, Springer, 2012.

    Peer-reviewed journal articles:

    • Franois, P., Altan-Bonnet, G., The case for absolute ligand discrimination: Modeling information processing and decision by immune T cells, Journal of Statistical Physics, 162:5 (mars 2016), 1130–1152.
    • Lalanne, J.-B., Francois, P., Chemodetection in fluctuating environments: Receptor coupling, buffering, and antagonism, Proceedings of the National Academy of Sciences of the United States of America, 112:6 (fvrier 2015), 1898–1903.
    • Francois, P., Evolving phenotypic network in silico, Seminars in Cell & Developmental Biology, 35 (novembre 2014), 90–97.
    • Lalanne, J.-B., Francois, P., Pinciples of adaptive sorting revealed by In Silico evolution , Physical Review Letters, 110 (mai 2013), 218102, 5p.
    • Francois, P., Voisinne, G., Siggia, E., Altan-Bonnet, G., Vergassola, M., Phenotypic model for early T-cell activation displaying sensitivity, specificity, and antagonism, Proceedings of the National Academy of Sciences of the United States of America, 110:10 (mars 2013), E888–897.

    • Lauschke, V. M., Tsiairis, C. D., Francois, P., Aulehla, A., Scaling of embryonic patterning based on phase-gradient encoding, Nature, 493:7430 (janvier 2013), 101–105.
    • Siggia, E., Francois, P., Phenotypic models of evolution and development: geometry as destiny , Current Opinion in Genetics & Development, 22:6 (dcembre 2012), 627–633.
    • Delaune, E. A., Francois, P., Shih, N. P., Amacher, S. L., Single-cell-resolution imaging of the impact of notch signaling and mitosis on segmentation clock dynamics, Developmental Cell, 23:5 (novembre 2012), 995–1005.
    • Francois, P., Despierre, N., Siggia, E., Adaptive temperature compensation in circadian oscillations, PLoS Computational Biology, 8:7 (juillet 2012), e1002585, 12p.
    • Warmflash, A., Francois, P., Siggia, E., Pareto evolution of gene networks: an algorithm to optimize multiple fitness objectives, Physical Biology, 9:5 (2012), 056001, 7p.

    Other journal articles:

    • Francois, P., Adaptation d’chelle et gradient de phase dans un modle ex vivo de somitogense, Mdicine/Sciences, 29:8-9 (2013 8), 696–698.
    • Delaune, E. A., Francois, P., Shih, N. P., Amacher, S. L., Une avance technique pour prendre la dynamique de l’horloge de segmentation, Mdicine/Sciences, 29:4 (avril 2013), 355–358.



    Frédéric Guichard

    Book chapters:

    • Le Corre, N., Guichard, F., Johnson, L. E., Connectivity as a management tool for coastal ecosystems in changing oceans, in Oceanography, Marco Marcelli, d., 2012.

    Peer-reviewed journal articles:

    • Guichard, F., The spatial dynamics of ecosystems, Advances in Ecology (XXXX), accept.
    • Pedersen, E., Marleau, J. N., Granados, M., Moeller, H., Guichard, F., Nonhierarchical dispersal promotes stability and resilience in a tritrophic metacommunity, The American Naturalist, 187:5 (mai 2016), E116–E128.
    • Xue, J. Z., Costopoulos, A., Guichard, F., A trait-based framework for mutation bias as a driver of long-term evolutionary trends, Complexity, 21:5 (2016), 331–345.
    • Marleau, J. N., Guichard, F., Loreau, M., Emergence of nutrient co-limitation through movement in stoichiometric meta-ecosystems, Ecology Letters, 18 (novembre 2015), 1163–1173.
    • Zhang, Y., Lutscher, F., Guichard, F., The effect of predator avoidance and travel time delay on the stability of predator-prey metacommunities, Theoretical Ecology, 8:3 (aot 2015), 273–283.
    • Zhang, Y., Lutscher, F., Guichard, F., How robust is dispersal-induced spatial synchrony?, Chaos, 25:3 (mars 2015), 036402, 8p.
    • Xue, J., Kaznatcheev, A., Costopoulos, A., Guichard, F., Fidelity drive: A mechanism for chaperone proteins to maintain stable mutation rates in prokaryotes over evolutionary time, Journal of Theoretical Biology, 364 (janvier 2015), 162–167.
    • Gounand, I., Mouquet, N., Canard, E., Guichard, F., Hauzy, C., Gravel, D., The paradox of enrichment in metaecosystems, The American Naturalist, 184:6 (dcembre 2014), 752–763.
    • Guichard, F., Gouhier, T. C., Non-equilibrium spatial dynamics of ecosystems, Mathematical Biosciences, 255 (septembre 2014), 1–10.
    • Gouhier, T. C., Guichard, F., Synchrony: quantifying variability in space and time, Methods in Ecology and Evolution, 5:6 (juin 2014), 524–533.
    • Kerr, K., Christy, J. H., Joly-Lopez, Z., Luque, J., Collin, R., Guichard, F., Reproducing on time when temperature varies: shifts in the timing of courtship by fiddler crabs, PLoS One, 9:5 (mai 2014), e97593, 11p.
    • Marleau, J. N., Guichard, F., Loreau, M., Meta-ecosystem dynamics and functioning on finite spatial networks, Proceedings of the Royal Society B. Biological Sciences, 281:1777 (janvier 2014), 20132094, 9p.
    • Kerr, K., Guichard, F., Collin, R., Cornejo, A., Planktonic predation risk varies with prey life history stage and diurnal phase, Marine Ecology Progress Series, 503 (2014), 99–109.
    • Wall, E., Guichard, F., Humphries, A. R., Synchronization in ecological systems by weak dispersal coupling with time delay, Theoretical Ecology, 6:4 (novembre 2013), 405–418.
    • Gouhier, T. C., Guichard, F., Menge, B. A., Designing effective reserve networks for nonequilibrium metacommunities, Ecological Applications, 23:6 (septembre 2013), 1488–1503.
    • Le Corre, N., Martel, A. L., Guichard, F., Johnson, L. E., Variation in recruitement: differentiating the roles of primary and secondary settlement of blue mussels Myrtilus spp, Marine Ecology Progress Series, 481 (mai 2013), 133–146.
    • Loreau, M., Daufresne, T., Gonzalez, A., Gravel, D., Guichard, F., Leroux, S., Loeuille, N., Massol, F., Mouquet, N., Unifying sources and sinks in ecology and Earth sciences, Biological reviews of the Cambridge Philosophical Society, 88:2 (mai 2013), 365–379.
    • Lacoursire-Roussel, A., Forrest, B. M., Guichard, F., Piola, R. F., McKindsey, C. W., Modeling biofouling from boat and source characteristics: a compartive study between Canada and New Zealand, Biological Invations, 14:11 (novembre 2012), 2301–2314.
    • Lacoursire-Roussel, A., Bock, D. G., Cristescu, M. E., Guichard, F., Girard, P., Legendre, P., McKindsey, C. W., Disentangling invasion processes in a dynamic shipping-boating network, Molecular Ecology, 21:17 (septembre 2012), 4227–4241.
    • Kerr, K., Christy, J. H., Collin, R., Guichard, F., Reducing error in reproductive timing causes by temperature variation: interspecific differences in behavioural adjustment by fiddler crabs, Marine Ecology Progress Series, 459 (juillet 2012), 1–16.
    • Pillai, P., Guichard, F., Competition-Colonizagtion trade-offs competitive uncertainty, and the evolutionary assembly of species, PLoS One, 7:3 (mars 2012), e33566.
    • Largaespada Roque, C., Guichard, F., Archambault, P., Meta-ecosystem engineering: nutrient fluxes reveal intraspecific and interspecific feedbacks in fragmented mussel beds, Ecology, 93:2 (fvrier 2012), 324–333.



    Antony R. Humphries

    Peer-reviewed journal articles:

    • Provencher Langlois, G., Craig, M., Humphries, A. R., Mackey, M. C., Mahaffy, J., Blair, J., Moulin, T., Sinclair, S. R., Wang, L., Normal and pathological dynamics of platelets in humans, Journal of Mathematical Biology, 75:6-7 (dcembre 2017), 1411–1462.
    • Calleja, R. C., Humphries, A. R., Krauskopf, B., Resonance phenomena in a scalar delay differential equation with two state-dependent delays, SIAM Journal on Applied Dynamical Systems, 16:3 (2017), 1474–1513.
    • Craig, M., Humphries, A. R., Mackey, M. C., A mathematical model of granulopoiesis incorporating the negative feedback dynamics and kinetics of G-CSF/neutrophil binding and internalization, Bulletin of Mathematical Biology, 78:12 (dcembre 2016), 2304–2357.
    • Humphries, A. R., Bernucci, D. A., Calleja, R. C., Homayounfar, N., Snarski, M., Periodic solutions of a singularly perturbed delay differential equation with two state-dependent delays, Journal of Dynamics and Differential Equations, 28:3-4 (septembre 2016), 1215–1263.
    • Craig, M., Humphries, A. R., Nekka, F., Blair, J., Li, J., Mackey, M. C., Neutrophil dynamics during concurrent chemotherapy and G-CSF administration: Mathematical modelling guides dose optimisation to minimise neutropenia, Journal of Theoretical Biology, 385 (novembre 2015), 77–89.
    • Wall, E., Guichard, F., Humphries, A. R., Synchronization in ecological systems by weak dispersal coupling with time delay, Theoretical Ecology, 6:4 (novembre 2013), 405–418.
    • Calleja, R., Doedel, E., Humphries, A. R., Lemus Rodriguez, A., Oldeman, B., Boundary-value problem formulations for computing invariant manifolds and connecting orbits in the circular restricted three body problem, Celestial Mechanics and Dynamical Astronomy, 114:1-2 (octobre 2012), 77–106.
    • Calleja, R. C., Doedel, E. J., Humphries, A. R., Lemus Rodriguez, A., Oldeman, B., Boundary-value problem formulations for computing invariant manifolds and connecting orbits in the circular restricted three body problem, Celestial Mechanics and Dynamical Astronomy, 114:1-2 (octobre 2012), 77–106.
    • Calleja, R. C., Doedel, E. J., Humphries, A. R., Lemus Rodriguez, A., Oldeman, B., Boundary-value problem formulations for computing invariant manifolds and connecting orbits in the circular restricted three body problem, Celestial Mechanics and Dynamical Astronomy, 114:1-2 (octobre 2012), 77–106.
    • Humphries, A. R., DeMasi, O., Magpantay, F., Upham, F., Dynamics of a delay differential equation with multiple state-dependent delays, Discrete and Continuous Dynamical Systems. Series A, 32:8 (aot 2012), 2701–2727.
    • De Luca, J., Humphries, A. R., Rodrigues, S. B., Finite element boundary value integration of Wheeler–Feynman electrodynamics, Journal of Computational and Applied Mathematics, 236:13 (juillet 2012), 3319–3337.



    Anmar Khadra

    Peer-reviewed journal articles:

    • Mitre, T. M., Pietropaolo, M., Khadra, A., The dual role of autoimmune regulator in maintaining normal expression level of tissue-restricted autoantigen in the thymus: a modeling investigation, Mathematical Biosciences, 287 (mai 2017), 12–23.
    • Mitre, T. M., Mackey, M. C., Khadra, A., Mathematical model of galactose regulation and metabolic consumption in yeast, Journal of Theoretical Biology, 407 (octobre 2016), 238–258.
    • Moran, S., Moenter, S. M., Khadra, A., A unified model for two modes of bursting in GnRH neurons, Journal of Computational Neuroscience, 40:3 (juin 2016), 297–315.
    • Jaberi Douraki, M., Pietropaolo, M., Khadra, A., Continuum model of T-cell avidity: understanding autoreactive and regulatory T-cell responses in type 1 diabetes, Journal of Theoretical Biology, 383 (octobre 2015), 93–105.
    • Jaberi Douraki, M., Schnell, S., Pietropaolo, M., Khadra, A., Unraveling the contribution of pancreatic beta-cell suicide in autoimmune type 1 diabetes, Journal of Theoretical Biology, 375 (juin 2015), 77–87.
    • Zemkova, H., Khadra, A., Rokic, M. B., Tvrdonava, V., Sherman, A., Stojilkovic, S. S., Allosteric regulation of the P2X4 receptor channel pore dilation , Pflgers Archiv – European Journal of Physiology, 467:4 (avril 2015), 713–726.
    • Morran, M. P., Vonberg, A., Khadra, A., Pietropaolo, M., Immunogenetics of type 1 diabetes mellitus, Molecular Aspects of Medicine, 42 (avril 2015), 42–60.
    • Jaberi Douraki, M., Wan, S., Pietropaolo, M., Khadra, A., Autoimmune responses in T1DM: quantitative methods to understand onset, progression, and prevention of disease, Pediatr Diabetes, 15:3 (mai 2014), 162–174.
    • Jaberi Douraki, M., Pietropaolo, M., Khadra, A., Predictive models of type 1 diabetes progression: Understanding T-Cell cycles and their implications on autoantibody release, PLoS One, 9:4 (avril 2014), e93326, 14p.
    • Khadra, A., Tomic, M., Yan, Z., Zemkova, H., Sherman, A., Stojilkovic, S. S., Dual gating mechanism and function of P2X7 receptor channels, Biophysical Journal, 104:12 (juin 2013), 2612–2621.
    • Sugarman, J., Tsai, S., Santamaria, P., Khadra, A., Quantifying the importance of pMHC valency, total pMHC dose and frequency on nanoparticle therapeutic efficacy, Immunology and Cell Biology, 91 (mars 2013), 350–359.
    • Khadra, A., Yan, Z., Coddou, C., Tomic, M., Sherman, A., Stojilkovic, S. S., Gating properties of the P2X2a and P2X2b receptor channels: experiments and mathematical modeling, The Journal of General Physiology, 139:5 (mai 2012), 333–348.



    Svetlana V. Komarova

    Peer-reviewed journal articles:

    • Boraschi-Diaz, I., Tauer, J. T., El-Rifai, O., Guillemette, D., Lefebvre, G., Rauch, F., Ferron, M., Komarova, S. V., Metabolic phenotype in the mouse model of osteogenesis imperfecta, Journal of Endocrinology, 234:3 (septembre 2017), 279–289.



    Frithjof Lutscher

    Book chapters:

    • Lutscher, F., Mathematics and biological diversity, in The Mathematics of Planet Earth: An International Year of Scientific and Outreach Activities, H. G.Karper, C. Rousseau, d., SIAM, 2015.
    • Wei, H.-H., Lutscher, F., From individual movement rules to population level patterns: the case of central place foragers, in Dispersal, Individual Movement and Spatial Ecology: A Mathematical Perspective, Lewis, M. A., Maini, P. K., Petrovskii, S. V., d., Lecture Notes in Mathematics, Vol. 2071, Berlin, Springer, 2013.
    • Bhunu, C. P., Tchuenche, J.-M., Lutscher, F., Mushayabasa, S., Bauch, C. T., Assessing the effect of drug abuse on the transmission dynamics of HIV/AIDS, in Understanding the Dynamics of Emerging and Re-emerging Infectious Diseases Using Mathematical Models, Bhunu, C. P., Mushayabasa, C., d., Trivandrum, Transworld Research Signpost, 2012.

    Peer-reviewed journal articles:

    • Dowdall, J., LeBlanc, V. G., Lutscher, F., Invasion pinning in a periodically fragmented habitat, Journal of Mathematical Biology, 77:1 (juillet 2018), 55–78.
    • de Boer, R., Lutscher, F., Choice disability as a target for non-medical HIV intervention, Mathematical Biosciences, 299 (mai 2018), 127–137.
    • Jin, Y., Lutscher, F., Pei, Y., Meandering rivers: How important is lateral variability for species persistence?, Bulletin of Mathematical Biology, 79:12 (dcembre 2017), 2954–2985.
    • Samia, Y., Lutscher, F., Downstream flow and upstream movement determine the value of a stream reach for potadromous fish populations, Theoretical Ecology, 10:1 (mars 2017), 21–34.
    • Tyson, R. C., Lutscher, F., Seasonally varying predation behaviour and climate shifts affect predator-prey cycles, The American Naturalist, 188:5 (novembre 2016), 539–553.
    • Vasilyeva, O., Lutscher, F., Lewis, M. A., Analysis of spread and persistence for stream insects with winged adult stages, Journal of Mathematical Biology, 72:4 (mars 2016), 851–875.
    • Lam, K.-Y., Lou, Y., Lutscher, F., The emergence of range limits in advective environments, SIAM Journal on Applied Mathematics, 76:2 (2016), 641–662.
    • Cobbold, C. A., Lutscher, F., Sherratt, J. A., Diffusion-driven instabilities and emerging spatial patterns in patchy landscapes, Ecological Complexity, 24 (dcembre 2015), 69–81.
    • Samia, Y., Lutscher, F., Hastings, A., Connectivity, passability and heterogeneity interact to determine fish population persistence in river networks, Journal of the Royal Society Interface, 12:110 (septembre 2015), 20150435.
    • Musgrave, J., Girard, A., Lutscher, F., Population spread in patchy landscapes under a strong Allee effect, Theoretical Ecology, 8:3 (aot 2015), 313–326.
    • Zhang, Y., Lutscher, F., Guichard, F., The effect of predator avoidance and travel time delay on the stability of predator-prey metacommunities, Theoretical Ecology, 8:3 (aot 2015), 273–283.
    • Zhang, Y., Lutscher, F., Guichard, F., How robust is dispersal-induced spatial synchrony?, Chaos, 25:3 (mars 2015), 036402, 8p.
    • Vasilyeva, O., Oraby, T., Lutscher, F., Aggregation and environmental transmission in chronic wasting disease, Mathematical Biosciences and Engineering, 12:1
      (fvrier 2015), 209–231.
    • Maciel, G. A., Lutscher, F., Allee effects and population spread in patchy landscapes, Journal of Biological Dynamics 9:1 (2015), 109–123.
    • Lam, K.-Y., Lou, Y., Lutscher, F., Evolution of dispersal in closed advective environments, Journal of Biological Dynamics 9:Suppl.1 (2015), 188–212.
    • Lou, Y., Lutscher, F., Evolution of dispersal in open advective environments, Journal of Mathematical Biology, 69:6-7 (dcembre 2014), 1319–1342.
    • Kanary, L., Musgrave, J., Tyson, R. C., Locke, A., Lutscher, F., Modelling the dynamics of invasion and control of competing green crab genotypes, Theoretical Ecology, 7:4 (novembre 2014), 391–404.
    • Musgrave, J., Lutscher, F., Integrodifference equations in patchy landscapes. II. Population level consequences, Journal of Mathematical Biology, 69:3 (septembre 2014), 617–658.
    • Musgrave, J., Lutscher, F., Integrodifference equations in patchy landscapes. I. Dispersal kernels, Journal of Mathematical Biology, 69:3 (septembre 2014), 583–615.
    • Lutscher, F., The interplay between mathematical and biological insight, CMS Notes/ Notes de la SMC, 46:3 (juin 2014), 16–17.
    • Cobbold, C. A., Lutscher, F., Mean occupancy time: linking mechanistic movement models, population dynamics and landscape ecology to population persistence, Journal of Mathematical Biology, 68:3 (fvrier 2014), 549–579.
    • Oraby, T., Vasilyeva, O., Krewski, D. R., Lutscher, F., Modeling seasonal behavior changes and disease transmission with application to chronic wasting disease, Journal of Theoretical Biology, 340 (janvier 2014), 50–59.
    • Maciel, G. A., Lutscher, F., How individual movement response to habitat edges affects population persistence and spatial spread, The American Naturalist, 182:1 (juillet 2013), 42–52.
    • Assaneo, F., Mendes Coutinho, R., Lin, Y., Mantilla, C., Lutscher, F., Dynamics and coexistence in a system with intraguild mutualism, Ecological Complexity, 14 (juin 2013), 64–74.
    • Erbach, A., Lutscher, F., Seo, G., Bistability and limit cycles in generalist predator–prey dynamics, Ecological Complexity, 14 (juin 2013), 48–55.
    • Leroux, S., Larrive, M., Boucher-Lalonde, V., Hurford, A., Zuloaga, J., Kerr, J. T., Lutscher, F., Mechanistic models for the spatial spread of species under climate change, Ecological Applications, 23:4 (juin 2013), 815–828.
    • Lutscher, F., Iljon, T., Competition, facilitation, and the Allee effect, Oikos, 122 (avril 2013), 621–631.
    • Lutscher, F., Nguyen, V. M., Traveling waves in discrete models of biological populations with sessile stages, Nonlinear Analysis. Real World Applications, 14:1 (fvrier 2013), 495–506.
    • Lutscher, F., McCauley, E., A probabilistic framework for nutrient uptake length, Theoretical Ecology, 6:1 (fvrier 2013), 71–81.
    • Vasilyeva, O., Lutscher, F., How flow speed alters competitive outcome in advective environments, Bulletin of Mathematical Biology, 74:12 (dcembre 2012), 2935–2958.
    • Vasilyeva, O., Lutscher, F., Competition of three species in an advective environment, Nonlinear Analysis. Real World Applications, 13:4 (aot 2012), 1730–1748.
    • Samia, Y., Lutscher, F., Persistence probabilities for stream populations, Bulletin of Mathematical Biology, 74:7 (juillet 2012), 1629–1650.
    • Hadeler, P.-K., Lutscher, F., Quiescent phases with distributed exit times, Discrete and Continuous Dynamical Systems. Series B, 17:3 (mai 2012), 849–869.
    • Al-Arydah, M. t., Smith, R. J., Lutscher, F., Modeling gender-structured wildlife diseases with harvesting: Chronic wasting dfisease as an example, ISRN Biomathematics, 2012 (2012), 802450, 18p.



    Michael C. Mackey

    Monographs and books:

    • Mackey, M. C., Santilln Zern, M., Tyran-Kaminska, M., Zeron, E. S., Simple Mathematical Models of Gene Regulatory Dynamics, Lecture Notes on Mathematical Modelling in the Life Sciences, Cham, Springer, 2016.

    Peer-reviewed journal articles:

    • De Souza, D. C., Mackey, M. C., Response of an oscillatory differential delay equation to a periodic stimulus, Journal of Mathematical Biology (XXXX), accept.
    • Zhuge, C., Mackey, M. C., Lei, J., Origins of oscillation patterns in cyclical thrombocytopenia, Journal of Theoretical Biology, 462 (fvrier 2019), 432–445.
    • Falfus, M., Mackey, M. C., Tyran-Kaminska, M., The combined effects of Feller diffusion and transcriptional/translational bursting in simple gene networks, Journal of Mathematical Analysis and Applications, 470:2 (fvrier 2019), 931–953.
    • Steward, C. G., Groves, S. J., Taylor, C. T., Maisenbacher, M. K., Versluys, B., Newbury-Ecob, R. A., Ozsahin, H., Damin, M. K., Bowen, V. M., McCurdy, K. R., Mackey, M. C., Bolyard, A. A., Dale, D. C., Neutropenia in Barth syndrome: characteristics, risks, and management, Current Opinion in Hematology, 26:1 (janvier 2019), 6–15.
    • Provencher Langlois, G., Arnold, D. M., Potts, J., Leber, B., Dale, D. C., Mackey, M. C., Cyclic thrombocytopenia with statistically significant neutrophil oscillations, Clinical Case Reports, 6:7 (juillet 2018), 1347–1352.
    • Provencher Langlois, G., Craig, M., Humphries, A. R., Mackey, M. C., Mahaffy, J., Blair, J., Moulin, T., Sinclair, S. R., Wang, L., Normal and pathological dynamics of platelets in humans, Journal of Mathematical Biology, 75:6-7 (dcembre 2017), 1411–1462.
    • Mackey, M. C., Tyran-Kaminska, M., Walther, H.-O., Response of an oscillatory differential delay equation to a single stimulus, Journal of Mathematical Biology, 74:5 (avril 2017), 1139–1196.
    • Craig, M., Humphries, A. R., Mackey, M. C., A mathematical model of granulopoiesis incorporating the negative feedback dynamics and kinetics of G-CSF/neutrophil binding and internalization, Bulletin of Mathematical Biology, 78:12 (dcembre 2016), 2304–2357.
    • Mitre, T. M., Mackey, M. C., Khadra, A., Mathematical model of galactose regulation and metabolic consumption in yeast, Journal of Theoretical Biology, 407 (octobre 2016), 238–258.
    • Self, J., Mackey, M. C., Random numbers from a delay equation, Journal of Nonlinear Science, 26:5 (octobre 2016), 1311–1327.
    • Mackey, M. C., Tyran-Kaminska, M., The limiting dynamics of a bistable molecular switch with and without noise, Journal of Mathematical Biology, 73:2 (aot 2016), 367–395.
    • Craig, M., Humphries, A. R., Nekka, F., Blair, J., Li, J., Mackey, M. C., Neutrophil dynamics during concurrent chemotherapy and G-CSF administration: Mathematical modelling guides dose optimisation to minimise neutropenia, Journal of Theoretical Biology, 385 (novembre 2015), 77–89.
    • Dale, D. C., Mackey, M. C., Understanding, treating and avoiding hematological disease: Better medicine through mathematics?, Bulletin of Mathematical Biology, 77:5 (mai 2015), 739–757.
    • Mackey, M. C., Maini, P., What has mathematics done for biology?, Bulletin of Mathematical Biology, 77:5 (mai 2015), 735–738.
    • Yvinec, R., Zhuge, C., Lei, J., Mackey, M. C., Adiabatic reduction of a model of stochastic gene expression with jump Markov process, Journal of Mathematical Biology, 68:5 (avril 2014), 1051–1070.
    • Riaz, S. S., Mackey, M. C., Dynamic spatial pattern formation in the sea urchin embryo, Journal of Mathematical Biology, 68:3 (fvrier 2014), 581–608.
    • Mackey, M. C., Santilln, M., Andre Fielding Huxley (1917-2012), Notices of the American Mathematical Society, 60:5 (mai 20133), 576–584.
    • Hilbert, L., Bates, G., Roman, H. N., Blumenthal, J. L., Zitouni, N. B., Sobieszek, A., Mackey, M. C., Molecular mechanical differences between isoforms of contractile actin in the presence of isoforms of smooth muscle tropomyosin, PLoS Computational Biology, 9:10 (octobre 2013), 1–9, e1003273.
    • Hilbert, L., Cumarasamy, S., Zitouni, N. B., Mackey, M. C., Lauzon, A.-M., The kinetics of mechanically coupled myosins exhibit group size-dependent regimes, Biophysical Journal, 105:6 (septembre 2013), 1466–1474.
    • Mackey, M. C., Tyran-Kaminska, M., Yvinec, R., Dynamic behavior of stochastic gene expression models in the presence of bursting, SIAM Journal on Applied Mathematics, 73:5 (2013), 1830–1852.
    • Brooks, G., Provencher Langlois, G., Lei, J., Mackey, M. C., Neutrophil dynamics after chemotherapy and G-CSF: the role of pharmacokinetics in shaping the response, Journal of Theoretical Biology, 315 (dcembre 2012), 97–109.
    • Apostu, R., Mackey, M. C., Mathematical model of GAL regulon dynamics in Saccharomyces cerevisiae, Journal of Theoretical Biology, 293 (janvier 2012), 219–235.
    • Zhuge, C., Lei, J., Mackey, M. C., Neutrophil dynamics in response to chemotherapy and G-CSF, Journal of Theoretical Biology, 293 (janvier 2012), 111–120.
    • Mackey, M. C., Tyran-Kaminska, M., Walther, H.-O., The mathematical legacy of Andrzej Lasota, Wiadomości Matematyczne, 48:2 (2012), 143–156.



    Fahima Nekka

    Peer-reviewed journal articles:

    • Wu, X., Nekka, F., Li, J., Steady-state volume of distribution of two-compartment models with simultaneous linear and saturated elimination, Journal of Pharmacokinetics and Pharmacodynamics, 43:4 (aot 2016), 447–459.
    • Craig, M., Gonzlez-Sales, M., Li, J., Nekka, F., Approaching pharmacometrics as a paleontologist would: Recovering the links between drugs and the body through reconstruction, CPT: Pharmacometrics & Systems Pharmacology, 5:3 (mai 2016), 158–160.
    • Craig, M., Humphries, A. R., Nekka, F., Blair, J., Li, J., Mackey, M. C., Neutrophil dynamics during concurrent chemotherapy and G-CSF administration: Mathematical modelling guides dose optimisation to minimise neutropenia, Journal of Theoretical Biology, 385 (novembre 2015), 77–89.
    • Sarem, S., Nekka, F., Ahmed, I. S., Litalien, C., Li, J., Impact of sampling time deviations on the prediction of the area under the curve using regression limited sampling strategies, Biopharmaceutics & Drug Disposition, 36:7 (octobre 2015), 417–428.
    • Sarem, S., Nekka, F., Barrire, O., Lapeyraque, A.-L., Duval, M., Teira, P., Bittencourt, H., Haddad, E., Thort, Y., Litalien, C., Limited sampling strategies for estimating intravenous and oral cyclosporine area under the curve in pediatric hematopoietic stem cell transplantation , Therapeutic Drug Monitoring, 37:2 (avril 2015), 198–205.
    • Wu, X., Li, J., Nekka, F., Closed form solutions and dominant elimination pathways of simultaneous first-order and Michaelis–Menten kinetics, Journal of Pharmacokinetics and Pharmacodynamics, 42:2 (avril 2015), 151–161.
    • Bonnefois, G., Barrire, O., Nekka, F., Li, J., A computational strategy for dose adaptation at the population and group levels, IOSR Journal of Pharmacy and Biological Sciences, 10:3 (2015), 52–63.
    • Sarem, S., Li, J., Barrire, O., Litalien, C., Thort, Y., Lapeyraque, A.-L., Nekka, F., Bayesian approach for the estimation of cyclosporine area under the curve using limited sampling strategies in pediatric hematopoietic stem cell transplantation, Theoretical Biology & Medical Modelling, 11 (septembre 2014), 39, 22p.
    • Barrire, O., Li, J., Nekka, F., Compliance spectrum as a drug fingerprint of drug intake and drug disposition, Journal of Pharmacokinetics and Pharmacodynamics, 40:1 (fvrier 2013), 41–52.
    • Li, J., Nekka, F., A rational quantitative approach to determine the best dosing regimen for a target therapeutic effect: a unified formalism for antibiotic evaluation, Journal of Theoretical Biology, 319 (fvrier 2013), 88–95.

    Peer-reviewed conference proceedings:

    • Li, J., Nekka, F., A spatial and nondegenerative autocorrelation function to reveal the inner similarity structure of irregular sets, in Emerging Applications of Wavelet Methods, 7th International Congress on Industrial and Applied Mathematics-Thematic Minisymposia, Siddiqi, A. H., d., AIP Conference Proceedings, Melvile, NY, Amer. Inst. Phys., 2012, 39–51.



    Christopher Pack

    Peer-reviewed journal articles:

    • Cook, E., Pack, C., Parietal cortex signals come unstuck in time, PLOS Biology, 10:10 (octobre 2012), e1001414.



    Lea Popovic

    Peer-reviewed journal articles:

    • Kumar, R., Popovic, L., Large deviations for multi-scale jump-diffusion processes, Stochastic Processes and their Applications, 127:4 (avril 2017), 1297–1320.
    • Popovic, L., Rivas, M., Topology and inference for Yule trees with multiple states, Journal of Mathematical Biology, 73:5 (novembre 2016), 1251–1291.
    • Pfaffelhuber, P., Popovic, L., Scaling limits of spatial compartment models for chemical reaction networks, The Annals of Applied Probability, 25:6 (dcembre 2015), 3162–3208.
    • Pfaffelhuber, P., Popovic, L., How spatial heterogeneity shapes multiscale biochemical reaction network dynamics, Journal of the Royal Society Interface, 12:104 (mars 2015), 20141106, 8p.
    • Popovic, L., Rivas, M., The coalescent point process of multi-type branching trees, Stochastic Processes and their Applications, 124:12 (dcembre 2014), 4120–4148.
    • McSweeney, J., Popovic, L., Stochastically-induced bistability in chemical reaction systems, The Annals of Applied Probability, 24:3 (mai 2014), 1226–1268.
    • Kang, H.-W., Kurtz, T. G., Popovic, L., Central limit theorems and diffusion approximations for multiscale Markov chain models, The Annals of Applied Probability, 24:2 (fvrier 2014), 721–759.
    • Lambert, A., Popovic, L., The coalescent point process of branching trees , The Annals of Applied Probability, 23:1 (fvrier 2013), 99–144.



    Alain Vinet

    Peer-reviewed journal articles:

    • Matene, E., Vinet, A., Jacquemet, V., Dynamics of atrial arrythmias modulated by time-dependent acetylcholine concentration: a simulation study, Europace, 16:4 (novembre 2014), iv11––iv20.
    • Xiong, F., Yin, Y., Dub, B., Pag, P., Vinet, A., Electrophysiological changes preceding the onset of atrial fibrillation after coronary bypass grafting surgery, PLoS One, 9:9 (septembre 2014), e107919, 3p.
    • Grgoire-Lacoste, F., Jacquemet, V., Vinet, A., Bifurcations, sustained oscillations and torus bursting involving ionic concentrations dynamics in a canine atrial cell model, Mathematical Biosciences, 250:10 (avril 2014), 10–25.
    • Jacquemet, V., Cassani, R., Sturmer, M., Dub, B., Sharestan, J., Vinet, A., Mahiddine, O., Leblanc, A.-R., Becker, G., Kus, T., Nadeau, R., QT internal measurement and correction in patients with atrial flutter: a pilot study, Journal of Electrocardiology, 47:2 (mars 2014), 228–235.
    • Sabouri, S., Matene, E., Vinet, A., Richer, L.-P., Cardinal, R., Armour, J. A., Pag, P., Kus, T., Jacquemet, V., Simultaneous epicardial and noncontact endocardial mapping of the canine right atrium: simulation and experiment, PLoS One, 9:3 (mars 2014), e91165, 11p.
    • Krouchev, N., Danner, S. M., Vinet, A., Rattay, F., Sawan, M., Energy-optimal electrical-stimulation pulses shaped by the least-action principle, PLoS One, 9:3 (mars 2014), e90480, 24p.
    • Beaumont, ., Salavatian, S., Southerland, M., Vinet, A., Jacquemet, V., Armour, J. A., Ardell, J. L., Network interactions within the canine intrinsic cardiac nervous system: implications for reflex control of regional cardiac function, The Journal of Physiology, 591:18 (septembre 2013), 4515–4533.
    • Cassani, R., Engels, E., Dub, B., Nadeau, R., Vinet, A., Leblanc, A.-R., Assessment of the sensitivity of detecting drug-induced QTc changes using subject-specific rate correction, Journal of Electrocardiology, 45:6 (novembre 2012), 541–545.