Activités scientifiques

Activités scientifiques

Séminaire à venir (1)

Ateliers et conférences passés (7)

Séminaires passés (78)

(à venir)

Le mardi 14 décembre 2021 – 12:00:00 – 13:00:00
Séminaire CAMBAM Seminar Series
En ligne/Web –

Top-down optimization recovers biological coding principles of single-neuron adaptation in RNNs

Guillaume Lajoie, University of Montreal

Site Web :

Spike frequency adaptation (SFA) is a well studied physiological mechanism with established computational properties at the single neuron level, including noise mitigating effects based on efficient coding principles. Network models with adaptive neurons have revealed advantages including modulation of total activity, supporting Bayesian inference, and allowing computations over distributed timescales. Such efforts are bottom-up, modeling adaptive mechanisms from physiology and analysing their effects. How top-down environmental and functional pressures influence the specificity of adaptation remains largely unexplored.

In this talk, I will discuss work where we use deep learning to uncover optimal adaptation strategies from scratch, in recurrent neural networks (RNNs) performing perceptual tasks. In our RNN model, each neuron’s activation function (AF) is taken from a parametrized family to allow modulation mimicking SFA, and an adaptation controller is trained end-to-end to control an AF in real time, based on pre-activation inputs to a neuron. Remarkably, we find emergent adaptation strategies that implement SFA mechanisms from biological neurons, including fractional input differentiation. This suggests that even in simplified models, environmental pressures and objective-based optimization are enough for sophisticated biological mechanisms to emerge.

Ateliers et conférences

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Date Titre Lieu Participants
2015/06/01 – 2015/06/12 The Joint 2015 CAMBAM-MBI-NIMBioS Summer School / Nonlinear Dynamics in Biological Systems McGill University
2017/06/12 – 2017/06/14 Translational-Oriented Quantitative Theurapeutic Approaches: A Concerted Effort Université de Montréal
2018/06/18 – 2018/06/29 The Joint CAMBAM/NSERC-CREATE in Complex Dynamics Summer School McGill University
2019/07/15 – 2019/07/19 Summer School on Nonlinear Dynamics in Life Sciences Fields Institute
2020/06/05 – 2020/06/05 CAMBAM Zoomposium: Multiple Timescales in Neuronal and Other Systems En ligne / Online
2020/07/27 – 2020/08/14 CAMBAM Workshops En ligne / Online
2021/05/31 – 2021/06/11 Summer School in Nonlinear Dynamics for the Life Sciences with Applications to Neuroscience and Psychology En ligne / Online


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Date Conférencier Titre Type
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2016/11/03 Mitchell Feigenbaum, Rockefeller University TBA Séminaire CAMBAM
2016/11/10 Sébastien Portalier, McGill University Physics, Body Size and the Structure of Food Webs Séminaire CAMBAM
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