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Theme Year 2000-2001

Mathematical Methods in Biology and Medicine

Graphic Design : Seyabec Inc. Illustrations courtesy of James P. Keener (Utah) and A.V. Pavilov (Utrecht) for the heart, and Georges Le Gouhaler (Montreal Neurological Institute) for the brain.

The year 2000-2001 at the CRM will be devoted to the rapidly developing field of mathematical methods in biology and medicine. The application of mathematics contributes to the understanding of natural processes both through mathematical models and their analysis, and through the development and application of mathematical methods of inference. The year emphasizes both aspects, with workshops covering various applications of nonlinear dynamics in biology and medicine, as well as genomics, and medical imaging.

Table of Contents Aisenstadt Chair Lecture Series Summer School International Annual Meetings Workshops Courses and Seminars Visitors Organizing Committee

Aisenstadt Chair Lecture Series

• Arthur T. Winfree (Arizona) : September 2000
  Vortices in Motionless Media
• Michael S. Waterman (USC) : March 2001
  Mathematics for Reading and Understanding Genetic Sequences

Summer School

• Nonlinear Dynamics in Biology and Medicine
  May 22 - June 3, 2000

  Offered jointly with the "Centre for Nonlinear Dynamics in Physiology and Medicine", this is an intensive introduction to the applications of nonlinear dynamics to biology and medicine, with computer exercices and an introduction to numerical techniques.

  Organizer : Jacques Bélair (Montréal)

  Instructors : M. Courtemanche (Montréal), E. Doedel (Concordia), L. Glass (McGill), M. Guevara (McGill), A. Longtin (Ottawa), M. C. Mackey (McGill), J. Milton (Chicago), A. Vinet (Montréal), J. Bélair (Montréal)

International Annual Meetings

• Combinatorial Pattern Matching (CPM 2000)
  June 21-23, 2000

  This meeting has a major computational biology component and includes fields which share a common focus on the formulation, algorithmic recognition, analysis, communication and storage of patterns in diverse kinds of data.

  Organizers : Raffaele Giancarlo (University of Palermo), David Sankoff (Montréal)

  Invited speakers : A. Broder (Altavista), F. Pereira (AT&T Labs), I. Witten (Waikato, New Zealand)

• Fifth Annual International Conference on Computational Molecular Biology (RECOMB 01)
  April 21-24, 2001

  The premier annual meeting in computational molecular biology, featuring a highly competitive selection of the best research papers from cutting edge projects for presentation, its subject is computational and mathematical in nature.

  Local organizer : David Sankoff (Montréal)

  For more information

Workshops

• Workshop on Bioinformatics
  17 May, 2000

  A workshop on diverse problem areas in bioinformatics, in the context of the annual meeting of the Association canadienne-française pour l'avancement des sciences (ACFAS).

  Organizer : Nadia El-Mabrouk (Montréal)

  Invited speakers : G. Butler (Concordia), G. Drouin (Ottawa), D. Forsdyke (Queen's), A. Kusalik (Saskatoon), M. Li (Waterloo), P. Rouzé (Ghent)

• Workshop on Novel Approaches in RNA Informatics (NARI)
  May 18-19, 2000

  The goal of this symposium is to explore the current state of the art in RNA informatics and to look towards the future of the field. The NARI symposium will provide a general forum for disseminating the latest developments, and will bring together scientists from biochemistry, molecular biology, computer science, mathematics and statistics who will present an overview of novel approaches.

  Organizer : François Major (Montréal)

  Invited speakers : C. Duarte (Columbia), A. Ellington (*) (Texas), R. Hughey (*) (UCSC), V. Mohan (Isis), E. Rivas (Washington), B. Shapiro (NCI), C. Wilson (UCSC)

  (*) to be confirmed

• Workshop on Molecular, Metabolic, and Gene Control Networks
  September 9-13, 2000

  Modeling in this field has recently considered topics including regulation of progression through the cell cycle as mediated by check points, control in the lactose and tryptophan operons, and the integrated behaviour of large coupled molecular/metabolic/gene networks. This workshop brings together both experimentalists and modelers to examine the current state of the field and the exciting future prospects.

  Organizer : Michael C. Mackey (McGill)

  Invited speakers : D. Bray (Cambridge), J. Collins (Boston), G. Church (Harvard), I. Epstein (Brandeis), J. Ferrell (*) (Stanford), L. Glass (McGill), A. Goldbeter (UL Bruxelles), H. Herzel (Berlin), K. Kohn (NIH), R. Larter (Purdue), S. Leibler (*) (Princeton), J. Mahaffy (San Diego State), J. Reinitz (Mt. Sinaï), J. Ross (Stanford), M. Roussel (Lethbridge), M. Santillan (Mexico City), M. Savageau (Michigan), S. Scott (Leeds), K. Showalter (West Virginia), P. Smolen (*) (Houston), R. Somogyi (Incyte), D. Thieffry (ULB), J. Tyson (Virginia), D. Wolf (Lawrence Livermore)

  (*) to be confirmed

  Registration

  Complete schedule

• Workshop on Gene Order Dynamics, Comparative Mapping and Multigene Families (DCAF)
  September 22-25, 2000
  (Le Chanteclerc, Ste-Adèle, Québec)

  This meeting will bring together scholars in the biological and mathematical sciences working on genome rearrangement, mapping and the evolution of gene families in human, animal, plant, other eukaryote, prokaryote, organellar and viral genomes.

  Organizers : David Sankoff (Montréal), Joseph H. Nadeau (Case Western Reserve University)

  Invited speakers : S. Anderson (Uppsala), V. Barriel (Paris) & C. Gallut (Paris), B. Bed'Hom (Paris), M. Blanchette (Seattle), J. Boore (Michigan), P. Bork (Heidelberg), D. Bryant (Montréal), G. Burger (Montréal), A. Caprara (Bologna) & G. Lancia (Padua), O. Cohen (Grenoble), K. Devos (UK), E. Eichler (Case Western Reserve), N. El-Mabrouk (Montréal), V. Ferretti (Montréal), A. Hughes, R. Irving (Glasgow), H.-P. Klenk (Gottingen), B. Koop (Victoria), D. Liben-Nowell (Cornell), L.A. Lyons (NIH), S.R. McCouch (Cornell), A. McLysaght (Dublin), S.M. McPeek (Chicago), J. Meidanis (Sao Paolo), A. Paterson (Georgia), J. Postlethwait (Oregon), D. Schoen (McGill), R. Shamir & I. Pe'er (Tel Aviv), M. Turmel (Laval), B. Trask (Seattle), D. Waddington (UK), J. Womack (Texas A&M)

  People interested in participating please contact David Sanfoff.

• Workshop on Nonlinear Dynamics and Biomathematics
  October 3-6, 2000

  The state of the art in the application of techniques from nonlinear dynamics to diverse fields of biology (biochemistry, physiology, resources management, medical imaging) will be covered. This workshop is part of the Entretiens du Centre Jacques-Cartier.

  Organizers : Pierre Auger (Lyon), Jacques Bélair (Montréal), Jacques Demongeot (Grenoble), Christiane Rousseau (Montréal)

  Invited speakers : O. Arino (Pau), P. Auger (Lyon), H. Benali (CHU Pitié Salpêtrière), A. Bourdou (INSERM), R. Bravo de la Parra (Alacala), F. Clarke (Lyon), J.-L. Coatrieux, J. Demongeot (Grenoble), A. Goldbeter (UL Bruxelles), R. Roussarie (Dijon), R. Thomas (UL Bruxelles), P. Tracqui (Grenoble), J. Bélair (Montréal), L. Gagnon (CRIM), L. Glass (McGill), B. Goulard (Montréal), J.-M. Lina (Montréal), S. Lessard (Montréal), A. Longtin (Ottawa), A. Vinet (Hôpital du Sacré-Coeur), N. Raissi (Maroc), D. Salahub (Institut Steacie), G. Wolkowicz (McMaster)

  There will be a poster session. If you want to present a poster please send title to Christiane Rousseau

  Registration

• Workshop on Memory, Delays and Multistability
  October 12-15, 2000

  This workshop will focus on recent advances in the mathematical modeling of neural systems in which one or more of the following are important features of the dynamics: 1) memory - in particular, "dynamic" memory, 2) propagation and synaptic delays, or 3) the coexistence of steady states. These features, as well as their possible interactions, have been highlighted in a number of recent studies across a variety of areas, namely in the context of the activity of recurrent neural circuits which are ubiquitous in the nervous system. The emphasis will be mainly on the mathematical modeling of real biological systems, yet the workshop will also explore the relevance of these issues to a range of disciplines ranging from psychology to artificial neural networks.

  Organizer : André Longtin (Ottawa)

  Conférenciers invités : K. Aihara (Tokyo), S. Becker (McMaster), S.A. Campbell (Waterloo), C. Canavier (New Orleans), G. Carpenter (Boston), A. Destexhe (CRNS, Gif-sur-Yvette, France), M. Ding (Florida Atlantic), R. Engbert (Postdam), U. Ernst (Bremen), R. Hahnloser (MIT), W. Gerstner (Lausanne), L. Glass (McGill), S.K. Han (Chungbuk, Corée du Sud), A. Herz (Humboldt-Berlin), E. Izhikevich (The Neurosciences Inst.), C. Laing (Pittsburg), W. Maass (Tech. U. Graz), J. Milton (Chicago), K. Pakdaman (INSERM), H. Wilson (York), J. Wu (York)

  (*) To be confirmed

  Abstracts

  Registration

  Complete schedule

  
  

• Workshop on Mapping and Control of Complex Arrhythmias
  October 29 - November 1, 2000

  This workshop will bring together mathematicians, experimentalists, physicians, and industrial representatives to present papers and discuss approaches to map and control complex arrhythmias. There will be a strong focus on novel interdisciplinary approaches to control atrial fibrillation.

  Organizer : Leon Glass (McGill)

  Invited speakers : M. Allessie (*) (Holland), D. Christini (New York), J. Collins (Boston), W. Ditto (*) (Georgia), A. Garfinkel (Los Angeles), P. Guerra (*) (Montréal), R. Ideker (Alabama), J. Jalife (*) (Syracuse), A. Karma (Boston), V. Krinsky (Nice), J. Leon (*) (Montréal), M. Lesh (San Francisco), R. Mehra (*) (Minneapolis), D. Nahon (*) (Montréal), S. Nattel (*) (Montréal), A. Panfilov (Holland), Y. Rudy (Cleveland), N. Trayanova (New Orleans), A. Vinet (Montréal), A. Winfree (*) (Arizona)

  (*) to be confirmed

  Supported in part by Guidant Corporation

  Registration

  Complete schedule

  
  

• Workshop on Fractal and Modeling in Structural and Dynamical Analysis
  November 11-14, 2000

  Classical problems in material sciences (surface characterization, description of branching networks) have been given new impetus by the introduction of fractal concepts. This workshop will cover the latest theoretical developments, their contributions in the biomedical field and future directions of investigations.

  Organizers : Jacques Bélair (Montréal), Fahima Nekka (Montréal)

  Invited speakers : Q. Cheng (York), A. Einstein (Mt. Sinaï), B.H. Kaye (Laurentian), S. Lubkin (North Carolina), H.E. Stanley (Boston), C. Tricot (Clermont-Ferrand), E. Vrscay (Waterloo), G. West (*) (Los Alamos)

  (*) to be confirmed

  For further information

  Registration

• Workshop on Mathematical Methods in Brain Mapping
  December 10-11, 2000

  Brain mapping is a rapidly growing research field that tries to understand human brain function and anatomy using 3D images from MRI, fMRI, PET, EEG and MEG using geometry, topology, statistics and random fields. This workshop is intended to bring together mathematicians and statisticians interested in brain mapping, and medical researchers interested in mathematical and statistical methods for the analysis of brain mapping data.

  Organizer : Keith Worsley (McGill)

  Invited speakers : J. Ashburner (UCL), J. Aston (London), H. Benali (CHU Pitié Salpêtrière), E. Brown (Harvard), A. Dale (Harvard), K. Friston (UCL), G. Glover (Stanford), L. K. Hansen (Tech. U. Denmark) , N. V. Hartvig (Aarhus), M. Hurdal (Florida State University), S. Kiebel (FSU jena), J.-F. Mangin (Service Hospitalier Frédéric Joliot, Orsay), J. Raz (U. Penn.), J. Riera (Cuban Neuroscience Center), J. Taylor (McGill), P. Thompson (UCLA)

  For more information

  Registration

• Workshop on Fractals and Wavelets in Medical Imaging
  February 26, 2001

  Organizer : Jean-Marc Lina (Montréal)

  Registration

• Workshop on Population Genetics at the Molecular Level
  March 9-11, 2001

  The genes and alleles of classical genetics are abstract notions. Now that these are increasingly understood in terms of particular sequences of DNA and protein, the mathematical foundations of the field must be revisited and expanded, which is the object of this workshop.

  Organizer : Brian Golding (McMaster)

  Invited speakers : L. Excoffier (Geneva), N. Goldman (*) (Cambridge), M. Gouy (Lyon), J. Huelsenbeck (Rochester), S. Kumar (Arizona State), S. Muse (NCSU), B. Rannala (Stony Brook), A. Rzhetsky (Columbia), J. Thorne (NCSU), Z. Yang (U.C.London)

  Full Schedule

  Registration

• Workshop on Mathematical Formalisms for RNA Structure
  April 26-27, 2001

  This symposium will explore the current state of the art in computational RNA structure, and provide a look towards the future of the field.

  Organizer : François Major (Montréal)

  Invited speakers : R. Altman (Stanford), J. Brown (NCSU), D. Case (Scripps), D. Gautheret (CNRS-Marseille), R. Gutell (Texas), S. Harvey (Alabama), D. Haussler (*), E. Westhof (CNRS-Strasbourg), M. Zuker (*) (St. Louis)

  (*) to be confirmed

  For any further information

Courses and Seminars

• Combinatorial Pattern Matching
  June 19-20, 2000

  Preceding CPM2000, this is a two-day tutorial on sequence analysis and other topics in computational biology and pattern matching.

  Organizer : David Sankoff (Montréal)

  Invited speakers : D. Bryant (Montréal), N. El-Mabrouk (Montréal), I. Witten (Waikato, New Zealand) and others

• Developing the Tools: A Canadian Bioinformatics Workshop
  June 26-July 1, 2000

  One of a series of training workshops piloted by the Canadian Genetic Diseases Network and the Biotechnology Human Resources Council.

  Organizers : Christopher Hogue (Toronto), François Major (Montréal)

• Biochemical and Chemical Kinetics
  September 7-8, 2000

  Preceding the workshop on Molecular, Metabolic, and Gene Control Networks, this course will introduce the basic concepts and techniques for the modeling of biochemical processes.

  Invited speakers : R. Larter (Purdue), S. Scott (Leeds), K. Shoewalter (West Virginia)

• Techniques in Brain Mapping
  December 5-8, 2000

  In preparation for the workshop on brain mapping, four series of introductory lectures will be given, covering the geometry of random field, methods in functional magnetic resonance imaging and methods for EEG analysis.

  Organizers : Keith Worsley (McGill), Bernard Goulard (Montréal)

  Invited speakers : R. Adler (TECHNION), H. Benali (CHU Pitié Salpêtrière), N. Lange (Harvard), P. Valdes (Cuban Neuroscience Center)

  For more information

  Fractals and Wavelets in Medical Imaging
  February 23 - 24, 2001

  Preceding the workshop, this tutorial will introduce the subject to nonspecialists.

  Organizers : Jean-Marc Lina (Montréal), Fahima Nekka (Montréal)

  Invited speaker : M. Unser (Swiss Federal Institute of Technology, Lausanne)

  For any further information

• Showcase for Competing Technologies for Phylogenetics (SCOPH)
  April 19-21, 2001

  This seminar is addressed to researchers, teachers and students interested in current developments in phylogenetic analysis. The speakers will each address one or two major areas and there will be ample time for comparison, debate and discussion. Some of the themes will be: efficient methods for very large phylogenies, model-based versus model-free approaches, tree inference with and without ancestor reconstruction, generalizations of trees. Software packages will be available on-line and there will be facilities for demonstrations and hands-on experimentation.

  Organizers : David Bryant (Montpellier), David Sankoff (Montréal)

  Invited speakers : D. Bryant (Montréal), A. Dress (Bielefeld), J. Felsenstein (Seattle), O. Gascuel (Montpellier), T. Hagedorn (College of New Jersey), K. Nixon (Cornell), M. Steel (Canterbury), D. Swofford (Cornell), T. Warnow

  For further information

Visitors

Support is available for short and long-term visits. Preference will be given to Junior investigators.

Organizing Committee

Jacques Bélair (Montréal)
Leon Glass (McGill)
Brian Golding (McMaster)
Leah Keshet (UBC)
David Sankoff (Montréal)
Keith Worsley (McGill)


Those wishing to participate in the above activities are invited to write to:

Louis Pelletier
Centre de recherches mathématiques (CRM)
Université de Montréal
C.P. 6128, Succ. Centre-ville
Montréal (Québec), CANADA H3C 3J7


E-mail: ACTIVITES@CRM.UMontreal.CA

August 9, 2001, webmaster@CRM.UMontreal.CA